BRIE: TRANSCRIPTOME-WIDE SPLICING QUANTIFICATION IN SINGLE CELLS

Abstract Single-cell RNA-seq (scRNA-seq) provides a comprehensive measurement of stochasticity in transcription, but the limitations of the technology have prevented its application to dissect variability candy button strips in RNA processing events such as splicing.Here, we present BRIE (Bayesian regression for isoform estimation), a Bayesian hier

Clostridium perfringens type C (Cp) is one of the principal microorganisms responsible for bacterial diarrhea in neonatal and pre-weaning piglets.To chiefs wine glass better understand the molecular effects of Cp infection, we performed a genome-wide comparison of the changes in DNA methylation and gene expression in Cp infected resistant and susce